How to Apply Plexaderm

Co-authored by Barbie Ritzman

Last Updated: December 7, 2024

Plexaderm is a skincare product that helps to reduce signs of aging, lessening the appearance of fine lines and wrinkles. Before you apply it, make sure your skin is clean and dry. Dispense a small drop out of the pump, gently spread onto areas on your face where you'd like to see improvement. It's important to let it set for 10 minutes, and you shouldn't move your facial muscles during this time.

Part 1

Part 1 of 2:

Preparing Your Skin and the Pump

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Wash your face to get rid of any leftover makeup, dirt, or oils. Use a facial soap and water to gently cleanse away any dirt or makeup from your face. Pay special attention to areas where you’ll be applying the Plexaderm, making sure these are clean.^{[1]
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- Leaving oil or skin care product residue under Plexaderm can make it less effective.
- It's a good idea to wash your hands as well, since you'll be applying the cream with your fingers.
Plexaderm won’t work properly unless your skin is completely dry. After you’ve washed it, blot your skin gently with a clean towel until it’s dry.^{[2]
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Prime the bottle before using it.^{[3]
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- Place the Plexaderm bottle on a flat, level surface and remove the cap.
- Using your thumb, slowly and firmly push the pump down until it cannot go any further.
- Continue pushing down the pump until product begins to flow, typically about 10-15 pumps; however, it could take longer so be patient.
- Once the desired amount of product has been dispensed, replace the cp for safe storage.
- Do not tamper with the self-sealing valve, as this could damage the pump.

Part 2

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Spreading the Plexaderm

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1
Press down on the pump to dispense a small drop onto your finger. Press down on it slowly to avoid squeezing out a large amount of Plexaderm—you’ll only want to use a small amount to start with. Dispense about half the size of a pea.
- Once the desired amount of product has been dispensed, replace the cap for safe storage.^{[4]
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Apply the Plexaderm to your skin using upward and outward strokes. Use your fingers to spread the Plexaderm over fine lines, wrinkles, and any puffy areas of your face or neck. Be careful to avoid your eyes, as it may irritate them.
- If Plexaderm does get in your eyes, rinse your eyes out with cool, clean water.
You don’t need to rub it until it dries on your skin, just make sure it’s evenly spread out in a thin layer. If you use too much, you’ll notice the white residue on your skin—you can gently dab this away with a damp cloth.
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Let the Plexaderm set for 5-10 minutes while remaining expressionless. While you can wait as little as 5 minutes, it’s best to wait 10 just to be sure the Plexaderm is working and has time to set. Don’t touch the spot where you applied it, and avoid talking, smiling, or moving your facial muscles.^{[5]
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- If you do move your face before the 10 minutes are up and break the bond, you can apply a little bit more and wait another 5 minutes.
- After the 10 minutes are up, you can move your face again.
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Reapply after 10 minutes if the first application doesn’t show results. If you don’t see any noticeable change, you can follow the same steps to apply the Plexaderm to the same spot again. It’s important to wait the full 10 minutes to be sure that you need to reapply.^{[6]
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- Only apply Plexaderm a second time if it’s really necessary—you don’t want to overuse the product on your skin.
- Overusing Plexaderm could cause your skin to look a bit unnatural, and excess product isn't good for the health of your skin.
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Use water-based moisturizers and makeup. Water-based products work best with Plexaderm.
- Use moisturizer at night, or at least 20 minutes before applying Plexaderm if you’re using them together.
- For makeup, try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip.^{[7]
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  Research source} Allow the Plexaderm mixture to set for 10 minutes. The ratio of Plexaderm to makeup ratio may vary depending on the brand of makeup.
Once the desired amount of the product has been dispensed, replace the cap and store the bottle at room temperature.

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Question

Can this cream be use on black skin?

Community Answer

Absolutely, with no difference whatsoever. Color of skin does not change the result at all.

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How do I avoid the darkness under the eyes after using Plexaderm on African-American skin tone?

Community Answer

After applying it, fan it out a little. Take a magazine, book, fan, or your hands. Then, if darker eye bags are still present, try adding a light foundation cream or eye bag concealer and applying it with your fingertips.

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I wear a moisturiser under makeup; when do I apply plexaderm, before my moisturizer or after?

Kelly S

Community Answer

It’s best to use a water-based moisturizer the night prior to use. If you deem moisturizer absolutely necessary, use a water-based product. Allow twenty minutes from the time of moisturizer application to the Plexaderm application.

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Tips

Plexaderm can last for up to 8 hours.

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Use Plexaderm anywhere on your face or neck, being careful to avoid your eyes.

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Rinse the product off whenever you'd normally wash your face, such as before bedtime.

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Warnings

Discontinue use if redness or irritation occurs.

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Avoid contact with the eyes. If eye contact occurs, flush gently and thoroughly with water.

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Keep out of reach of children.

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