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Obagi is the brand name for a line of skin care products that offers prescription-strength ingredients. Obagi products are only available through a doctor or specialty medical spa; products sold by retailers (in-store and online) are re-selling the products without authorization and there is no guarantee the products are genuine. Obagi products are divided into five groups: transformation systems, essential products, targeted solutions, skin recovery, and in-office procedures (i.e. not for home use).

Method 1
Method 1 of 2:

Using the Obagi Nu-Derm® System

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  1. Start by cleansing your face with the gentle cleanser (normal to dry skin) or foaming gel (normal to oily skin). This cleanser is designed to remove everyday dirt, grime, and makeup from your skin. The cleanser will leave you with a clean and fresh complexion.
    • Use the cleanser twice a day, once during your morning routine and again during your nighttime routine.
  2. After cleansing, apply the toner (same product for all skin types) to your skin in order to re-balance the pH levels of your skin. The toner is designed not to dry out your skin.
    • Use the toner twice a day, once during your morning routine and again during your nighttime routine.
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  3. “Clear” contains prescription-strength hydroquinone. “Clear” is designed to help correct the various discolourations on your skin to leave you with a more even skin tone. The same product is used for all skin types.
    • The “Clear” product is only available by prescription.
    • Be sure to talk with your doctor about the use of hydroquinone and its potential side effects.
    • Use the “Clear” product twice a day, once during your morning routine and again during your nighttime routine.
  4. Exfoderm® (for normal to dry skin) or Exfoderm® Forte (for normal to oily skin), is designed to exfoliate the skin on your face to help remove dead skin cells. This type of exfoliation helps to reveal newer skin cells which help give you a brighter and clearer complexion.
    • Use Exforderm® only once a day, during your morning routine.
  5. Blender® also contains prescription-strength hydroquinone. Blender® is designed to gradually lighten your skin in order to remove age or sun spots and other types of discolouration that may appear on your face. The same product is used for all skin types.
    • Blender® is available only by prescription.
    • Be sure to talk with your doctor about the use of hydroquinone and its potential side effects.
    • Use Blender® only once a day, during your nighttime routine.
  6. Hydrate™ is designed to help moisturize and hydrate the dry and flaky parts of the skin on your face. You only need to use Hydrate™ if you find these dry areas. The same product is used for all skin types.
    • Use Hydrate™ as needed during either your morning or nighttime routine.
  7. If you are using any of the Obagi systems that includes a product with hydroquinone it is essential that you always use sunscreen on your face. Unfortunately hydroquinone causes even the smallest amount of exposure to sunlight to create a melanocytic activity, which in turn can cause skin cancer. Obagi offers a product called Sun Shield Matte Broad Spectrum SPF 50 specifically designed to be used with the Obagi systems. It offers both UVA and UVB protection for your skin, and comes in a sheer, matte finish.
    • This sunscreen can be used on all skin types.
    • Sunscreen only needs to be applied after you've completed your morning routine. You do not need to apply sunscreen before you go to bed.
  8. Obagi's also had three products which can be used in conjunction with the Nu-Derm® System.
    • Sunfader® is a cream product that can be used as the last step (before sunscreen) to target specific discoloured spots on your face. It contains SPF 15 and 4% hydroquinone to help correct and even out those discoloured spots. Sunfader® is only available with a prescription.
    • If you use Sunfader®, use it only once a day as part of your morning routine.
    • Healthy Skin Protection SPF 35 is a sunscreen that also contains 9% micronized zinc oxide and 7.5% octinoxate. It provides broad spectrum UVA and UVB protection and can be used instead of Sun Shield Matte Broad Spectrum SPF 50.
    • Physical SPF 32 is a sunscreen with 18.5 zinc oxide that provides broad spectrum UVA and UVB protection. It can be used instead of Sun Shield Matte Broad Spectrum SPF 50.
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Method 2
Method 2 of 2:

Learning About Other Obagi Transformation Systems

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  1. Start by using the Exfoliating Cleanser to wash and clear your skin of dirt and dead skin cells. The cleanser will make your skin look soft and smooth. Then add the Retinol 0.5% cream. The Retinol 0.5% product gradually releases the retinol throughout the day to help you skin become brighter and to reduce the signs of aging. The end result is that your skin will look smoother and clearer. The third step is to add the HydraFactor Broad Spectrum SPF 30 sunscreen. This sunscreen contains both a moisturizer and a sunscreen and will keep your skin both hydrated and protected from the sun.[1]
    • This product is designed for all skin types.
    • This product is designed for younger patients.
    • As an alternative, you can also choose the Retinol 1.0% product. With double the retinol content, the 1.0% solution helps to minimize fine lines, reduce wrinkles, refine your skin's complexion, and smooth your skin's texture.
  2. System for acne-prone skin. The CLENZlderm M.D. System is designed specifically for people with normal to oily skin who also suffer from acne. The system starts with the Daily Care Foaming Cleanser, which contains 2% salicylic acid. The cleanser is to be used twice daily (morning and night) and unclogs pores in order to leave skin feeling fresh. The second step in the system is the Pore Therapy, which also contains 2% salicylic acid. Pore Therapy is designed to prepare your skin for step 3, which is the Therapeutic Lotion. The Therapeutic Lotion contains 5% BPO which also helps to clean up acne.[2]
    • In addition to these three products, you can also get the Therapeutic Moisturizer, which contains 20% glycerin. This product leaves you skin moisturized and keeps it soothed during the full acne treatment.
    • BPO is benzoyl peroxide.
  3. This system is designed specifically for people with sensitive skin. The first step is the Soothing Cleanser which will cleanse your skin while soothing it at the same time. The second step is the Skin Calming Cream which hydrates your skin and helps eliminate the signs of aging. The third step is the Fortified Sunscreen Broad Spectrum SPF 30 with Vitamin C which works to protect your skin from sun damage. The Fortified Sunscreen contains 10% L-ascorbic acid, which is also known as Vitamin C. The fourth step is the Advanced Night Repair cream which helps keep your skin moisturized while you sleep.
    • The Fortified Sunscreen Broad Spectrum SPF 30 with Vitamin C only needs to be used during your morning routine.
    • The Advanced Night Repair cream only needs to be used during your nighttime routine.
    • As an alternative to the Skin Calming Cream you can choose the Skin Calming Lotion. The lotion is a lighter version which will help soothe your sensitive skin and keep it hydrated.
    • You can also add the Skin Rejuvenation Serum to your routine. This serum works with your skin's natural rejuvenation abilities to help speed up the healing process of prematurely aged skin.
    • As an alternative to the Fortified Sunscreen Broad Spectrum SPF 30 with Vitamin C you can choose the Ultra-Light Repair SPF 30 Sunscreen Cream. In addition to being a sunscreen, this cream helps to repair your skin and reduce the signs of early aging.
    • You can also add the Ultra-Rich Eye Hydrating Cream to your routine. This cream is specifically designed to repair the damage to the skin around your eyes.
  4. This system is designed to help reduce the early signs of aging that may have been caused by sun damage. The first step is the C-Cleansing Gel which helps to remove oil, grime, and makeup from your face and prepares your skin for the remaining steps. If you have normal to oily skin your second step will be the C-Balancing Toner which will help balance your skin's pH levels. If you have normal to dry skin, the C-Clarifying Serum will be your second step; if you have normal to oil skin, it'll be your third step. The Serum helps to smooth out the dark spots on your skin. If you have normal to dry skin, the next step is the C-Exfoliating Day Lotion. This lotion is a light moisturizer that both hydrates and exfoliates your skin to leave it fresh and healthy. The next step for all skin types is the Sun Shield Broad Spectrum SPF 50 which contains both UVA and UVB protection to help keep your skin safe against the sun. The final step for all skin types is the C-Therapy Night Cream which helps keep your skin hydrated and protected while you sleep.
    • The C-Clarifying Serum is available only by prescription.
    • The Sun Shield Broad Spectrum SPF 50 only needs to be used during your morning routine.
    • The C-Therapy Night Cream only needs to be used during your nighttime routine. It is only available by prescription.
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Tips

  • Always wash your hands before and after using any of the products with hydroquinone. Be careful not to get any in your eyes, nose, or mouth.[3]
  • Do not use products with hydroquinone on areas of your face which may be cut, scraped, or burned.
  • Always wear protective clothing in addition to sunscreen when outdoors. Items like hats, sunglasses, long-sleeve shirts, etc., will also help protect your skin from sun damage. It's also a good idea to use a lip balm with SPF — you can wear the lip balm under your regular lipstick or lip gloss if you'd like.
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Warnings

  • Do not use any other products with the Obagi systems. You should also use all products that are part of the six step system (Nu-Derm® System) in order to achieve the best results.
  • You will most likely experience redness, flaking, and dryness during the first few weeks of treatment. You will also likely see your skin problems get worse during this time, instead of better. This is considered normal and should be explained to you by your doctor.
  • The Nu-Derm® System can take 6-8 weeks to fully restore your skin. After this time you should discuss your maintenance routine with your doctor.
  • Some Obagi products are not available in some states, specifically MA, MT, NH, NY, and TX, because those states do not permit physicians to sell prescriptions through their medical offices. The “Nu-Derm Fx System” is sold as an non-prescription alternative for customers who are not able to purchase the prescription-strength versions.[4]
  • Hydroquinone is a somewhat controversial drug which has been banned Canada, Europe, and Japan. It is currently undergoing an intensive review by the Federal Drug Administration (FDA) in the U.S. to determine if it should be considered as “generally safe and effective.” As of right now it is still available in the U.S., but this could change pending the results of the FDA's investigations.[5]
  • The Obagi “Clear” product contains sodium metabisulfite which can cause allergic reactions in some people. These allergic reactions could include anaphylactic symptoms and life-threatening asthmatic episodes. The level of sulfite sensitivity in the general population is not known, and is likely more prevalent in people who suffer from asthma.
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About This Article

Zora Degrandpre, ND
Co-authored by:
Natural Health Doctor
This article was co-authored by Zora Degrandpre, ND. Dr. Zora Degrandpre is a Natural Health Doctor and Licensed Naturopathic Physician in Vancouver, Washington. She is a grant reviewer for the National Institutes of Health and the National Center for Complementary and Alternative Medicine. She received her ND from the National College of Natural Medicine in 2007. This article has been viewed 131,512 times.
36 votes - 94%
Co-authors: 11
Updated: March 11, 2024
Views: 131,512
Categories: Skin Care Products
Article SummaryX

To use Obagi, start by washing your face with either the gentle cleanser or the foaming gel. Then, apply the toner to your skin, followed by the "Clear" product, which will help with discoloration and uneven skin tone. Next, exfoliate your skin with the "Exfoderm" product if you're doing your morning routine, or apply the "Blender" product if you're doing your nightly routine. Finally, if you have any dry or flaky areas on your face, apply the "Hydrate" product to them to help moisturize your skin. To learn how to use other Obagi systems, scroll down!

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Thanks to all authors for creating a page that has been read 131,512 times.

Reader Success Stories

  • Donna Spinelli

    Donna Spinelli

    Jan 1, 2017

    "Did 18 weeks, 67 years old, and what a difference. Yes, face red and raw, but oh so worth it. I am on maintenance..." more
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