How to Use Vagisil

Co-authored by Carrie Noriega, MD

Last Updated: August 21, 2024 Fact Checked

Vagisil is a commercial, over-the-counter topical cream that relieves vaginal itching. Vagisil is available as a regular-strength or maximum-strength cream. It is easy to use, but there are a few precautions to keep in mind when you use it.

Part 1

Part 1 of 2:

Using Vagisil

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Using too much Vagisil can lead to severe side effects, so only apply a small amount. The amount of Vagisil cream that you use should be about as long as your fingertip (about one inch long).^{[1]
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Apply Vagisil to the outside of your genitals (vulva) only. Do not insert Vagisil into your vagina. Only use it on the parts of your vagina that are outside of your body, such as your labia and vulva. Use your finger to rub the cream into the outer areas of your vagina to help soothe itching.^{[2]
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- Do not apply Vagisil to large areas of your body. Applying Vagisil to large areas of your body may cause severe side effects, so only use it on the affected areas of your vagina. If your itching extends beyond the area that a small amount of Vagisil will cover, then call your doctor or gynecologist.
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The product works by blocking the nerve signals that cause itching. This will provide some temporary relief from vaginal itching.^{[3]
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Research source} Just keep in mind that it might take a few minutes for the medicine to work, so try to be patient.
You should not use Vagisil more than four times per day. If you still have symptoms after using Vagisil, then contact your doctor or gynecologist.^{[4]
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Research source} You may require a prescription strength medication.

Part 2

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Knowing When to Seek Help

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1
Seek immediate medical attention for serious side effects. The active medicine in Vagisil (benzocaine) can cause some severe side effects, but only when used in the mouth; however, seek emergency medical treatment if you experience any of the following symptoms:^{[5]
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- Light-headedness
- Fast heart rate
- Shortness of breath
- Bluish, grayish, or pale lips, fingernails, or skin
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Watch for signs of an allergic reaction. Benzocaine topical can also cause an allergic reaction for some people. Stop using Vagisil and call your doctor if you notice:^{[6]
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- Severe stinging, burning, or sensitivity
- Swelling, redness, or warmth
- Oozing
- Blistering
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Look for common side effects. Some side effects are normal, so do not panic if you notice some mild side effects from using Vagisil. Common side effects of using Vagisil include:^{[7]
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- Minor burning or itching
- Mild redness or tenderness
- White, dry flakes at application site
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Call your doctor if your symptoms do not improve. Vagisil is meant for temporary, short-term use only. If your symptoms last for more than seven days and they do not seem to be getting better, then call your doctor or gynecologist.^{[8]
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- Vagisil is not designed to treat itching caused by an infection. If you have signs of an infection, like abnormal vaginal discharge, odor, or open sores in the area, then you should seek medical care instead of using Vagisil.

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Question

Can you use it for chafing?

Carrie Noriega, MD
Board Certified Obstetrician & Gynecologist
Dr. Noriega is a Board Certified Obstetrician & Gynecologist and medical writer in Colorado. She specializes in women’s health, rheumatology, pulmonology, infectious disease, and gastroenterology. She received her MD from the Creighton School of Medicine in Omaha, Nebraska and completed her residency at the University of Missouri - Kansas City in 2005.

Carrie Noriega, MD

Board Certified Obstetrician & Gynecologist

Expert Answer

You can use it for chafing but a product like A&D ointment, designed for irritation in this area, will probably work better.

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I had swelling and itchiness when I applied Vagisil the last time. The only way to get the swelling down was to put ice on it with a small towel. What does this mean?

Carrie Noriega, MD
Board Certified Obstetrician & Gynecologist
Dr. Noriega is a Board Certified Obstetrician & Gynecologist and medical writer in Colorado. She specializes in women’s health, rheumatology, pulmonology, infectious disease, and gastroenterology. She received her MD from the Creighton School of Medicine in Omaha, Nebraska and completed her residency at the University of Missouri - Kansas City in 2005.

Carrie Noriega, MD

Board Certified Obstetrician & Gynecologist

Expert Answer

If Vagisil caused swelling and itching, you should not use it again. You are most likely allergic to something in the cream. If the symptoms went away when you iced the area then you don't need to do anything else. If this did not improve the symptoms you need to see a doctor for additional treatment.

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Vagisil is recommended for people who suffer from vaginal itching caused by antibiotics, vaginal discharge, an imbalance in pH, and other irritating vaginal conditions. Consult with your healthcare provider immediately if Vagisil does not provide relief for your vaginal itching.

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Warnings

Do not take Vagisil without consulting with your healthcare provider if you smoke, have heart disease, suffer from a respiratory disorder such as asthma, emphysema, or bronchitis, or have a family history of enzyme deficiency.^{[9]
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Research source} Vagisil could have adverse effects on your overall health if you suffer from any of these conditions.

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